A transient rise in plasma beta-endorphin after a traditional 47 degrees C hot-spring bath in Kusatsu-spa, Japan.

Authors: Kubota K (1) , Kurabayashi H (1) , Tamura K (1) , Kawada E (1) , Tamura J (1) , Shirakura T (1)
Affiliations:
(1) Department of Medicine, Kusatsu Branch Hospital, Gunma University School of Medicine
Source: Life Sci. 1992;51(24):1877-80.
DOI: 10.1016/0024-3205(92)90039-R Publication date: 1992 E-Publication date: Not specified Availability: full text Copyright: © 1992 Pergamon Press Ltd All rights reserved.
Language: English Countries: Japan Location: Kusatsu Spa Correspondence address: Kubota K. :
Department of Medicine, Kusatsu Branch Hospital, Gunma University School of Medicine, Japan

Keywords

Article abstract

To clarify the mechanism of the intoxicating feeling attained after a traditional 47 degrees C hot-spring bath called 'jikan-yu' in Kusatsu-spa, Japan, we examined the change in plasma levels of beta-endorphin and methionine enkephalin in 7 healthy subjects. The mean sublingual temperature rose from 36.8 degrees C to 38.6 degrees C and the plasma beta-endorphin level from 16.2 pg/ml to 49.5 pg/ml 2 minutes after completing a 3-minute bath in 47 degrees C hot-spring water. However, the plasma methionine enkephalin level was not changed. This feeling of intoxication may be explained by the transient rise in plasma beta-endorphin level.

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